The effect of pre- and after-treatment of sevoflurane on central ischemia tolerance and the underlying mechanisms
Xu Hao, Mei Xiao-Peng, Xu Li-Xian,
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( Xu Hao ) - Xian Medical University Institution of Basic Medical Science
( Mei Xiao-Peng ) - Xi¡¯an Jiaotong University First Affiliated Hospital Department of Anesthesiology
( Xu Li-Xian ) - Fourth Military Medical University School of Stomatology Department of Anesthesiology
Abstract
In recent years, with continuous research efforts targeted at studying the effects of pre- and after-treatment of inhaled anesthetics, significant progress has been made regarding the common clinical use of low concentrations of inhaled sevoflurane and its effect on induced central ischemia tolerance by pre- and post-treatment. In this study, we collected, analyzed, classified, and summarized recent literature regarding the effect of sevoflurane on central ischemia tolerance and its related mechanisms. In addition, we provide a theoretical basis for the clinical application of sevoflurane to protect the central nervous system and other important organs against ischemic injury.
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Central Nervous System; Ischemia; Sevoflurane; Tolerance
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